Acetyl Tetrapeptide-2 for Sleep
Anti-aging tetrapeptide marketed for thymopoietic skin remodeling and firmness.
Why Acetyl Tetrapeptide-2 for sleep?
Acetyl Tetrapeptide-2 is marketed by Lipotec/Lubrizol under the trade name Uplevity. Manufacturer-funded clinical data report improved skin firmness and reduced sagging via thymopoietic-pathway mimicry. Independent peer-reviewed evidence is limited, and effects are generally modest like other cosmetic peptides.
Sleep context: Modulating sleep architecture, slow-wave sleep depth, and circadian regulation. Acetyl Tetrapeptide-2 fits this goal because its category (Cosmetic) and benefit profile align with the underlying mechanism.
Benefits relevant to sleep
- Skin firmness
- Reduces sagging around eyes
- Marketed as 'thymus-mimetic'
Reference dosing by bodyweight
Anchored to the most-cited research dose (250 mcg @ 75 kg). Reference only.
| Bodyweight band | Reference dose range |
|---|---|
| <60 kg / <132 lb | 156–211 mcg |
| 60–75 kg / 132–165 lb | 191–259 mcg |
| 75–90 kg / 165–198 lb | 234–316 mcg |
| 90–105 kg / 198–231 lb | 276–374 mcg |
| >105 kg / >231 lb | 319–431 mcg |
Side effects to weigh against sleep benefit
- Localized sensitivity (rare)
Also researched for
Educational use only
This calculator is provided for research and educational purposes. Outputs are derived from the values you enter. Always verify your math and consult a licensed physician before acting on any result.