Medication Storage Calculator
Predict stability days remaining for lyophilized or reconstituted peptides. Enter your storage condition and reconstitution date to see the projected expiration window and any storage recommendations.
Medication Storage Calculator
Predicts remaining stability window based on storage condition, reconstitution status, and literature defaults. Manufacturer or COA data always supersedes these estimates.
The date you mixed the peptide with diluent.
Recommendations
- The 28-day in-use limit for bacteriostatic-water-preserved reconstitutions is an industry standard matching FDA-approved GLP-1 prescribing information. It applies regardless of peptide type when specific data is unavailable.
Note: Conservative defaults based on pharmaceutical literature and FDA prescribing information. Manufacturer or compounding pharmacy COA data always supersedes these estimates.
How stability windows are calculated
This tool applies literature-derived stability defaults and, where available, data from FDA-approved prescribing information for peptide drugs. All outputs are predicted stability windows based on conservative pharmaceutical defaults and industry-standard compounding guidelines. They are not guarantees of potency.
Manufacturer guidance always supersedes this calculator. If your compounding pharmacy provides a beyond-use date (BUD) on the vial label, that date takes precedence. If you are using a brand-name pen product such as Ozempic, Wegovy, Mounjaro, or Zepbound, follow the in-use instructions in the prescribing information, not this tool.
Key stability principles
- Lyophilized (freeze-dried) peptides are far more stable than reconstituted solutions. At -20°C, pharmaceutical-grade lyophilized peptides routinely achieve 24-month stability.
- The 28-day limit for bacteriostatic-water-reconstituted peptides is not specific to any one peptide. It is the universal in-use standard for benzyl-alcohol-preserved multi-dose vials, mirrored in FDA prescribing information for GLP-1 agonists.
- Sterile water without a preservative has a dramatically shorter window: USP guidelines allow a maximum of 24 hours for Category 1 compounded sterile preparations without antimicrobial agents when stored refrigerated.
- Never freeze a reconstituted peptide solution. Ice crystal formation during freeze-thaw cycles can irreversibly disrupt peptide secondary structure.
- Temperature excursions (brief periods outside the recommended range) accelerate degradation and are not accounted for in this model. If a vial has experienced extended room-temperature exposure, treat the stability window as shortened.
Sources cited in this tool
- Ozempic (semaglutide) US Prescribing Information, Novo Nordisk (2023): 28-day in-use limit, refrigerated or room temperature.
- Mounjaro (tirzepatide) US Prescribing Information, Eli Lilly (2022): 28-day in-use limit.
- Egrifta SV (tesamorelin) US Prescribing Information, Theratechnologies (2019): reconstitute immediately before use; use within 3 hours.
- Genotropin (somatropin) US Prescribing Information, Pfizer (2022): 21-day refrigerated stability with bacteriostatic diluent.
- USP Chapter 797, Pharmaceutical Compounding (2023): Category 1 CSP beyond-use dates without antimicrobial preservative.
- Manning et al., Pharmaceutical Research (2010): “Stability of Protein Pharmaceuticals.”
Frequently asked questions
Educational use only
This calculator is provided for research and educational purposes. Outputs are derived from the values you enter. Always verify your math and consult a licensed physician before acting on any result.