N-Acetyl Semax · Cognitive
N-Acetyl Semax dosage by bodyweight
Reference dose ranges scaled across bodyweight bands, anchored to the most-cited research dose (300 mcg @ 75 kg). Educational only, never a recommendation.
| Bodyweight band | Reference dose range | At U-100 (1 mg/mL) | Vol. on U-100 (5 mg / 2 mL) | 5× t½ elapsed |
|---|---|---|---|---|
| <60 kg / <132 lb | 187–253 mcg | 0.19–0.25 mL | 8–10 units0.07–0.10 mL | – |
| 60–75 kg / 132–165 lb | 230–311 mcg | 0.23–0.31 mL | 9–12 units0.09–0.12 mL | – |
| 75–90 kg / 165–198 lb | 281–379 mcg | 0.28–0.38 mL | 11–15 units0.11–0.15 mL | – |
| 90–105 kg / 198–231 lb | 332–448 mcg | 0.33–0.45 mL | 13–18 units0.13–0.18 mL | – |
| >105 kg / >231 lb | 383–518 mcg | 0.38–0.52 mL | 15–21 units0.15–0.21 mL | – |
Volume column assumes a standard 5 mg vial reconstituted with 2 mL bacteriostatic water (concentration 2.5 mg/mL); insulin units shown for a U-100 syringe. No published half-life on file for N-Acetyl Semax; the elapsed-time column is hidden.
Dose & PK references
Selected from the N-Acetyl Semax bibliography for relevance to dosing and pharmacokinetics.
- Semax, an ACTH(4-10) analogue with nootropic properties, activates dopaminergic and serotoninergic brain systems in rodents
- Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus
- The neuroprotective effects of Semax in conditions of MPTP-induced lesions of the brain dopaminergic system
Educational use only
This calculator is provided for research and educational purposes. Outputs are derived from the values you enter. Always verify your math and consult a licensed physician before acting on any result.