Pal-GHK for Libido
Lipidated GHK tripeptide; the second active in Matrixyl 3000 stack.
Why Pal-GHK for libido?
Pal-GHK (palmitoyl tripeptide-1) couples palmitic acid to glycyl-L-histidyl-L-lysine for improved skin penetration of the GHK signaling motif. Combined with pal-GHK-OH (palmitoyl tetrapeptide-7) it forms the Matrixyl 3000 complex marketed by Sederma. Most data come from manufacturer-funded ex vivo and clinical evaluation.
Libido context: Modulating melanocortin / kisspeptin pathways relevant to sexual response and arousal. Pal-GHK fits this goal because its category (Cosmetic) and benefit profile align with the underlying mechanism.
Benefits relevant to libido
- Stimulates collagen
- Improves elasticity
- Pairs with pal-GHK-OH
Reference dosing by bodyweight
Anchored to the most-cited research dose (250 mcg @ 75 kg). Reference only.
| Bodyweight band | Reference dose range |
|---|---|
| <60 kg / <132 lb | 156–211 mcg |
| 60–75 kg / 132–165 lb | 191–259 mcg |
| 75–90 kg / 165–198 lb | 234–316 mcg |
| 90–105 kg / 198–231 lb | 276–374 mcg |
| >105 kg / >231 lb | 319–431 mcg |
Side effects to weigh against libido benefit
- Mild local irritation (rare)
Educational use only
This calculator is provided for research and educational purposes. Outputs are derived from the values you enter. Always verify your math and consult a licensed physician before acting on any result.