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Performance · For Muscle Gain

MK-677 (Ibutamoren) for Muscle Gain

Oral GH secretagogue that cranks appetite, muscle preservation, and bone density.

Why MK-677 (Ibutamoren) for muscle gain?

MK-677 signals the pituitary gland to secrete growth hormone. It acts as a potent, orally active growth hormone secretagogue.

Muscle Gain context: Increasing lean mass via GH/IGF-1 axis, satellite-cell activity, or anabolic signaling. MK-677 (Ibutamoren) fits this goal because its category (Performance) and benefit profile align with the underlying mechanism.

Benefits relevant to muscle gain

  • Increases muscle mass

Reference dosing by bodyweight

Anchored to the most-cited research dose (10000 mcg @ 75 kg). Reference only.

Bodyweight bandReference dose range
<60 kg / <132 lb62338433 mcg
60–75 kg / 132–165 lb765010350 mcg
75–90 kg / 165–198 lb935012650 mcg
90–105 kg / 198–231 lb1105014950 mcg
>105 kg / >231 lb1275017250 mcg

Side effects to weigh against muscle gain benefit

  • Increased appetite
  • Water retention
  • Lethargy
  • Decreased insulin sensitivity
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Full bodyweight chart
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MK-677 (Ibutamoren) guide

Also researched for

Educational use only

This calculator is provided for research and educational purposes. Outputs are derived from the values you enter. Always verify your math and consult a licensed physician before acting on any result.