LL-37 Truncated Variants (KR-12 / KS-30)
Shorter active fragments of LL-37 (KR-12, KS-30) with retained antimicrobial activity but lower toxicity.
No acute perceptible effect; reported benefits build over days to weeks of consistent use.
Store the lyophilized powder refrigerated (2 to 8 C), or frozen for long-term storage, protected from light. After reconstitution with bacteriostatic water, keep refrigerated and use within about 4 weeks.
Clinical Evidence
What the literature says
Scientific Overview
KR-12 (residues 18-29 of LL-37) is the smallest active fragment retaining antimicrobial activity, identified by Wang et al. (2008). KS-30 and other truncations balance efficacy with reduced cytotoxicity vs full-length LL-37. Investigated for chronic-wound, biofilm, and dental indications; no approved human indication yet.
Citations (4)
- Antimicrobial Peptides of the Cathelicidin Family: Focus on LL-37 and Its ModificationsPubMed
- The structure of the antimicrobial human cathelicidin LL-37 shows oligomerization and channel formation in the presence of membrane mimicsReview
- Antimicrobial and Chemoattractant Activity, Lipopolysaccharide Neutralization, Cytotoxicity, and Inhibition by Serum of Analogs of Human Cathelicidin LL-37Review
- LL-37, the only human member of the cathelicidin family of antimicrobial peptidesReview
Research Guide
How users approach this compound
The following reflects patterns observed in research literature and community protocols. This is not medical advice and does not constitute a clinical recommendation.
Research Protocols
Common DosagesResearch
“Topical/research only”
Dosages listed are common research protocols found in peer-reviewed literature and clinical trials. Individual results and requirements may vary significantly in a research context.
Key Research Benefits
- Antimicrobial activity preserved
- Lower hemolysis vs full LL-37
- Wound healing research
Potential Side Effects
Labs to monitor
Educational context only, not a testing mandate. Any bloodwork decisions belong with your clinician.
- No validated compound-specific markers: No standard bloodwork is established for this compound; general safety labs (CBC, comprehensive metabolic panel) are reasonable if used under medical supervision.
Dose Calculator
Peptide Reconstitution Calculator
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Stack LL-37 Truncated Variants (KR-12 / KS-30)with…
Curated stacking partners researched alongside LL-37 Truncated Variants (KR-12 / KS-30). Each link opens a dedicated stack page with combined benefits, side-effect overlap, and half-life considerations.
- Performance stackLL-37 Truncated Variants (KR-12 / KS-30) + IpamorelinGentle GH releaser that amps muscle growth and fat loss without the harsh sides.
- Performance stackLL-37 Truncated Variants (KR-12 / KS-30) + CJC-1295Pairs with Ipamorelin for sustained growth hormone spikes, ideal for body comp tweaks.
- Performance stackLL-37 Truncated Variants (KR-12 / KS-30) + SermorelinMimics natural GH pulses to build lean mass and improve sleep/recovery.
- Performance stackLL-37 Truncated Variants (KR-12 / KS-30) + MK-677 (Ibutamoren)Oral GH secretagogue that cranks appetite, muscle preservation, and bone density.
LL-37 Truncated Variants (KR-12 / KS-30) by goal
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Not medical advice
Information on DoseVault is for educational purposes only and is not a substitute for medical advice, diagnosis, or treatment from a qualified healthcare provider.