Is PT-141 (Bremelanotide) researched for libido?

PT-141 (Bremelanotide) is a Cosmetic compound. Melanocortin agonist FDA-approved (Vyleesi) for HSDD; libido enhancement. For libido specifically, the relevant mechanism is modulating melanocortin / kisspeptin pathways relevant to sexual response and arousal.

What is the typical research dose of PT-141 (Bremelanotide) for libido?

1.0–1.75 mg ≥45 min before activity, Max 1 dose/24h, 8 doses/month.

What side effects of PT-141 (Bremelanotide) matter most when used for libido?

Nausea; Flushing; BP elevation (transient)

Cosmetic · For Libido

PT-141 (Bremelanotide) for Libido

Melanocortin agonist FDA-approved (Vyleesi) for HSDD; libido enhancement.

Why PT-141 (Bremelanotide) for libido?

Bremelanotide (Vyleesi) is FDA-approved for premenopausal HSDD. Acts on MC4R in the hypothalamus.

Libido context: Modulating melanocortin / kisspeptin pathways relevant to sexual response and arousal. PT-141 (Bremelanotide) fits this goal because its category (Cosmetic) and benefit profile align with the underlying mechanism.

Benefits relevant to libido

Increases libido

Reference dosing by bodyweight

Anchored to the most-cited research dose (1000 mcg @ 75 kg). Reference only.

Bodyweight band	Reference dose range
<60 kg / <132 lb	623–843 mcg
60–75 kg / 132–165 lb	765–1035 mcg
75–90 kg / 165–198 lb	935–1265 mcg
90–105 kg / 198–231 lb	1105–1495 mcg
>105 kg / >231 lb	1275–1725 mcg

Side effects to weigh against libido benefit

Nausea
Flushing
BP elevation (transient)
Headache

Calculator

Reconstitute PT-141 (Bremelanotide)

Reference

Full bodyweight chart

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PT-141 (Bremelanotide) guide

Also researched for

PT-141 (Bremelanotide) for Sleep

Educational use only

This calculator is provided for research and educational purposes. Outputs are derived from the values you enter. Always verify your math and consult a licensed physician before acting on any result.