Tripeptide-1 (GHK) for Libido
Free GHK tripeptide (Gly-His-Lys), the parent motif of GHK-Cu skincare actives.
Why Tripeptide-1 (GHK) for libido?
Tripeptide-1 is the INCI name for free GHK (Gly-His-Lys), originally identified by Pickart in 1973 as a plasma factor that improves liver-cell function with age. In topicals it is most often paired with copper to form GHK-Cu, but free GHK is widely used as a cosmetic active claiming collagen and elastin upregulation. Most evidence is industry-funded.
Libido context: Modulating melanocortin / kisspeptin pathways relevant to sexual response and arousal. Tripeptide-1 (GHK) fits this goal because its category (Cosmetic) and benefit profile align with the underlying mechanism.
Benefits relevant to libido
- Stimulates collagen and elastin
- Improves skin texture
- Wound-healing signaling
Reference dosing by bodyweight
Anchored to the most-cited research dose (250 mcg @ 75 kg). Reference only.
| Bodyweight band | Reference dose range |
|---|---|
| <60 kg / <132 lb | 156–211 mcg |
| 60–75 kg / 132–165 lb | 191–259 mcg |
| 75–90 kg / 165–198 lb | 234–316 mcg |
| 90–105 kg / 198–231 lb | 276–374 mcg |
| >105 kg / >231 lb | 319–431 mcg |
Side effects to weigh against libido benefit
- Mild local sensitivity (rare)
Also researched for
Educational use only
This calculator is provided for research and educational purposes. Outputs are derived from the values you enter. Always verify your math and consult a licensed physician before acting on any result.