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CagriSema (Cagrilintide + Semaglutide) · Metabolic

CagriSema (Cagrilintide + Semaglutide) dosage by bodyweight

Reference dose ranges scaled across bodyweight bands, anchored to the most-cited research dose (4000 mcg @ 75 kg). Educational only, never a recommendation.

Bodyweight bandReference dose rangeAt U-100 (1 mg/mL)Vol. on U-100 (5 mg / 2 mL)5× t½ elapsed
<60 kg / <132 lb24933373 mcg2.493.37 mL100135 units1.001.35 mL
60–75 kg / 132–165 lb30604140 mcg3.064.14 mL122166 units1.221.66 mL
75–90 kg / 165–198 lb37405060 mcg3.745.06 mL150202 units1.502.02 mL
90–105 kg / 198–231 lb44205980 mcg4.425.98 mL177239 units1.772.39 mL
>105 kg / >231 lb51006900 mcg5.106.90 mL204276 units2.042.76 mL

Volume column assumes a standard 5 mg vial reconstituted with 2 mL bacteriostatic water (concentration 2.5 mg/mL); insulin units shown for a U-100 syringe. No published half-life on file for CagriSema (Cagrilintide + Semaglutide); the elapsed-time column is hidden.

CagriSema (Cagrilintide + Semaglutide) by goal

Read CagriSema (Cagrilintide + Semaglutide)'s profile and dosing through a specific research-goal lens.

Dose & PK references

Selected from the CagriSema (Cagrilintide + Semaglutide) bibliography for relevance to dosing and pharmacokinetics.

  1. Coadministered Cagrilintide and Semaglutide in Adults with Overweight or Obesity (REDEFINE 1)
  2. Cagrilintide plus semaglutide 2.4 mg, Phase 1b safety/PK/PD
  3. REDEFINE 1 trial record (NCT05567796)

Educational use only

This calculator is provided for research and educational purposes. Outputs are derived from the values you enter. Always verify your math and consult a licensed physician before acting on any result.