Magainin 2 · Other
Magainin 2 dosage by bodyweight
Reference dose ranges scaled across bodyweight bands, anchored to the most-cited research dose (250 mcg @ 75 kg). Educational only, never a recommendation.
| Bodyweight band | Reference dose range | At U-100 (1 mg/mL) | Vol. on U-100 (5 mg / 2 mL) | 5× t½ elapsed |
|---|---|---|---|---|
| <60 kg / <132 lb | 156–211 mcg | 0.16–0.21 mL | 6–8 units0.06–0.08 mL | – |
| 60–75 kg / 132–165 lb | 191–259 mcg | 0.19–0.26 mL | 8–10 units0.08–0.10 mL | – |
| 75–90 kg / 165–198 lb | 234–316 mcg | 0.23–0.32 mL | 9–13 units0.09–0.13 mL | – |
| 90–105 kg / 198–231 lb | 276–374 mcg | 0.28–0.37 mL | 11–15 units0.11–0.15 mL | – |
| >105 kg / >231 lb | 319–431 mcg | 0.32–0.43 mL | 13–17 units0.13–0.17 mL | – |
Volume column assumes a standard 5 mg vial reconstituted with 2 mL bacteriostatic water (concentration 2.5 mg/mL); insulin units shown for a U-100 syringe. No published half-life on file for Magainin 2; the elapsed-time column is hidden.
Dose & PK references
Selected from the Magainin 2 bibliography for relevance to dosing and pharmacokinetics.
- Review: Examining the Natural Role of Amphibian Antimicrobial Peptide Magainin
- The cationic peptide magainin II is antimicrobial for Burkholderia cepacia-complex strains
- Highly synergistic antimicrobial activity of magainin 2 and PGLa peptides is rooted in the formation of supramolecular complexes with lipids
Educational use only
This calculator is provided for research and educational purposes. Outputs are derived from the values you enter. Always verify your math and consult a licensed physician before acting on any result.