Pal-GHK
Lipidated GHK tripeptide; the second active in Matrixyl 3000 stack.
Topical effects build gradually over weeks of consistent use.
Topical and cosmetic formulations: store per the product directions, typically cool and away from light; follow any beyond-use date.
Clinical Evidence
What the literature says
Scientific Overview
Pal-GHK (palmitoyl tripeptide-1) couples palmitic acid to glycyl-L-histidyl-L-lysine for improved skin penetration of the GHK signaling motif. Combined with pal-GHK-OH (palmitoyl tetrapeptide-7) it forms the Matrixyl 3000 complex marketed by Sederma. Most data come from manufacturer-funded ex vivo and clinical evaluation.
Research Guide
How users approach this compound
The following reflects patterns observed in research literature and community protocols. This is not medical advice and does not constitute a clinical recommendation.
Research Protocols
Common DosagesTopical
“Leave-on; combine with pal-GHK-OH”
Dosages listed are common research protocols found in peer-reviewed literature and clinical trials. Individual results and requirements may vary significantly in a research context.
Key Research Benefits
- Stimulates collagen
- Improves elasticity
- Pairs with pal-GHK-OH
Potential Side Effects
Labs to monitor
Educational context only, not a testing mandate. Any bloodwork decisions belong with your clinician.
- No validated compound-specific markers: No standard bloodwork is established for this compound; general safety labs (CBC, comprehensive metabolic panel) are reasonable if used under medical supervision.
Dose Calculator
Peptide Reconstitution Calculator
Total amount of peptide in the vial.
Volume of water used to mix.
Draw to this mark
or 0.10 mL on a U-100 syringe
Pal-GHK by goal
Read Pal-GHK's profile filtered through specific research goals.
Related Tools
Not medical advice
Information on DoseVault is for educational purposes only and is not a substitute for medical advice, diagnosis, or treatment from a qualified healthcare provider.