ARA-290 (Cibinetide) vs Sermorelin
ARA-290 (Cibinetide): Investigational 11-amino-acid peptide derived from the helix-B region of erythropoietin that activates the innate repair receptor without stimulating red-blood-cell production; studied for small-fiber neuropathy.
Sermorelin: Mimics natural GH pulses to build lean mass and improve sleep/recovery.
ARA-290 (Cibinetide)
RecoveryInvestigational 11-amino-acid peptide derived from the helix-B region of erythropoietin that activates the innate repair receptor without stimulating red-blood-cell production; studied for small-fiber neuropathy.
Top benefits
- Activates the innate repair receptor to promote tissue protection and healing
- Reduced neuropathic pain symptoms in sarcoidosis small-fiber neuropathy trials
- Increased corneal nerve fiber measures (a marker of small-nerve regeneration) without raising hematocrit
Sermorelin
PerformanceMimics natural GH pulses to build lean mass and improve sleep/recovery.
Top benefits
- Increases lean body mass
- Improves sleep quality
- Reduces body fat
- Enhances immune function
| Attribute | ARA-290 (Cibinetide) | Sermorelin |
|---|---|---|
| Category | Recovery | Performance |
| Type | linear | linear |
| Chain length | 11 aa | 29 aa |
| Formula | helix-B 11-mer (non-erythropoietic EPO derivative) | C149H246N44O42S |
| Common dose | 2 mg IV or 1-8 mg SC | 200-500 mcg |
| Frequency | Three times weekly to daily (per trial) | Daily (at bedtime) |
| Top benefit | Activates the innate repair receptor to promote tissue protection and healing | Increases lean body mass |
| Top side-effect | Generally well tolerated in trials | Flushing |
Educational use only
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