Metabolic effects build over days to weeks of consistent use.
Store the lyophilized powder refrigerated (2 to 8 C), or frozen for long-term storage, protected from light. After reconstitution with bacteriostatic water, keep refrigerated and use within about 4 weeks.
Clinical Evidence
What the literature says
Scientific Overview
Selective NNMT inhibitor; depletes the methyl-sink pathway and elevates intracellular SAM and NAD+. Animal data shows fat-mass reduction without diet change.
Citations (5)
- Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in micePubMed
- Reduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in DIO micePubMed
- Nicotinamide N-methyltransferase inhibition mitigates obesity-related metabolic dysfunctionPubMed
- Roles of Nicotinamide N-Methyltransferase in Obesity and Type 2 DiabetesReview
- Nicotinamide N-methyltransferase (NNMT): a novel therapeutic target for metabolic syndromeReview
Research Guide
How users approach this compound
The following reflects patterns observed in research literature and community protocols. This is not medical advice and does not constitute a clinical recommendation.
Research Protocols
Common DosagesDaily
“Oral; cycle 4–8 weeks”
Dosages listed are common research protocols found in peer-reviewed literature and clinical trials. Individual results and requirements may vary significantly in a research context.
Potential Side Effects
Labs to monitor
Educational context only, not a testing mandate. Any bloodwork decisions belong with your clinician.
- No validated compound-specific markers: No standard bloodwork is established for this compound; general safety labs (CBC, comprehensive metabolic panel) are reasonable if used under medical supervision.
Dose Calculator
Peptide Reconstitution Calculator
Total amount of peptide in the vial.
Volume of water used to mix.
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5-Amino-1MQ by goal
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Not medical advice
Information on DoseVault is for educational purposes only and is not a substitute for medical advice, diagnosis, or treatment from a qualified healthcare provider.