MOTS-c · Longevity
MOTS-c dosage by bodyweight
Reference dose ranges scaled across bodyweight bands, anchored to the most-cited research dose (5000 mcg @ 75 kg). Educational only, never a recommendation.
| Bodyweight band | Reference dose range | At U-100 (1 mg/mL) | Vol. on U-100 (5 mg / 2 mL) | 5× t½ elapsed |
|---|---|---|---|---|
| <60 kg / <132 lb | 3117–4217 mcg | 3.12–4.22 mL | 125–169 units1.25–1.69 mL | – |
| 60–75 kg / 132–165 lb | 3825–5175 mcg | 3.83–5.17 mL | 153–207 units1.53–2.07 mL | – |
| 75–90 kg / 165–198 lb | 4675–6325 mcg | 4.67–6.33 mL | 187–253 units1.87–2.53 mL | – |
| 90–105 kg / 198–231 lb | 5525–7475 mcg | 5.53–7.47 mL | 221–299 units2.21–2.99 mL | – |
| >105 kg / >231 lb | 6375–8625 mcg | 6.38–8.63 mL | 255–345 units2.55–3.45 mL | – |
Volume column assumes a standard 5 mg vial reconstituted with 2 mL bacteriostatic water (concentration 2.5 mg/mL); insulin units shown for a U-100 syringe. No published half-life on file for MOTS-c; the elapsed-time column is hidden.
MOTS-c by goal
Read MOTS-c's profile and dosing through a specific research-goal lens.
Dose & PK references
Selected from the MOTS-c bibliography for relevance to dosing and pharmacokinetics.
- Reduced serum and skeletal muscle MOTS-c levels in women with polycystic ovary syndrome are associated with mitochondrial dysfunction
- The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance
- The mitochondrial-derived peptide MOTS-c is a regulator of plasma metabolites and enhances insulin sensitivity
Educational use only
This calculator is provided for research and educational purposes. Outputs are derived from the values you enter. Always verify your math and consult a licensed physician before acting on any result.