BPC-157
BPC-157 is a 15-amino-acid sequence derived from human gastric juice protein. It has been studied for its ability to promote angiogenesis and upregulate growth factor expression at injury sites. Preclinical research suggests it modulates nitric oxide signaling and activates the FAK-paxillin pathway involved in cell migration and tissue repair.
No acute perceptible effect; reported tissue-repair benefits build over days to weeks of consistent use.
Store the lyophilized powder refrigerated (2 to 8 C), or frozen for long-term storage, protected from light. After reconstitution with bacteriostatic water, keep refrigerated and use within about 4 weeks.
Clinical Evidence
What the literature says
Scientific Overview
Derived from a protein found in stomach acid, BPC-157 has shown remarkable properties in healing soft tissue injuries in animal models, including tendon-to-bone healing and superior ligament healing.
Pharmacokinetics
- Half-life (t½)
- 4 h
- Approximate plasma half-life
- Routes
- SubcutaneousIntramuscularOral
t½ 4 h · ~3% remaining at 20 h
Citations (7)
- From Regeneration to Analgesia: The Role of BPC-157 in Tissue Repair and Pain ManagementPubMed 2026
- Achilles detachment in rat and stable gastric pentadecapeptide BPC 157: Promoted tendon-to-bone healing and opposed corticosteroid aggravationPubMed
- Protective effects of pentadecapeptide BPC 157 on gastric ulcer in ratsPubMed
- BPC 157 and Standard Angiogenic Growth Factors. Gastrointestinal Tract Healing, Lessons from Tendon, Ligament, Muscle and Bone HealingPubMed
- Stable Gastric Pentadecapeptide BPC 157 and Wound HealingPubMed
- Modulatory effect of gastric pentadecapeptide BPC 157 on angiogenesis in muscle and tendon healingPubMed
- Stable gastric pentadecapeptide BPC 157: novel therapy in gastrointestinal tractPubMed
Last reviewed: 2026-05-09
Research Guide
How users approach this compound
The following reflects patterns observed in research literature and community protocols. This is not medical advice and does not constitute a clinical recommendation.
Typical Dose Range Observed
Research Protocols
Common DosagesStandard Repair
“Subcutaneous injection or oral (stable version)”
Dosages listed are common research protocols found in peer-reviewed literature and clinical trials. Individual results and requirements may vary significantly in a research context.
Reported Uses
- Studied for soft-tissue and tendon injury recovery in preclinical models
- Investigated for potential gastrointestinal mucosal protection
- Explored for anti-inflammatory properties in animal research
Key Research Benefits
- Speeds up tendon healing
- Accelerates muscle recovery
- Promotes gut healing
- Reduces inflammation
Potential Side Effects
Considerations and Cautions
- No human safety data from controlled trials; use in humans is off-label and experimental
- Theoretical caution in active malignancy given pro-angiogenic properties
Labs to monitor
Educational context only, not a testing mandate. Any bloodwork decisions belong with your clinician.
- No validated compound-specific markers: No standard bloodwork is established for this compound; general safety labs (CBC, comprehensive metabolic panel) are reasonable if used under medical supervision.
Dose Calculator
Peptide Reconstitution Calculator
Total amount of peptide in the vial.
Volume of water used to mix.
Draw to this mark
or 0.10 mL on a U-100 syringe
Quick Explainer
Stack BPC-157with…
Curated stacking partners researched alongside BPC-157. Each link opens a dedicated stack page with combined benefits, side-effect overlap, and half-life considerations.
- Performance stackBPC-157 + IpamorelinGentle GH releaser that amps muscle growth and fat loss without the harsh sides.
- Performance stackBPC-157 + CJC-1295Pairs with Ipamorelin for sustained growth hormone spikes, ideal for body comp tweaks.
- Performance stackBPC-157 + SermorelinMimics natural GH pulses to build lean mass and improve sleep/recovery.
- Performance stackBPC-157 + MK-677 (Ibutamoren)Oral GH secretagogue that cranks appetite, muscle preservation, and bone density.
BPC-157 by goal
Read BPC-157's profile filtered through specific research goals.
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Not medical advice
Information on DoseVault is for educational purposes only and is not a substitute for medical advice, diagnosis, or treatment from a qualified healthcare provider.