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111 compounds across peptides, hormones, and small molecules. 52 have full evidence profiles with mechanism summaries, evidence grades, and peer-reviewed citations. Information is for educational purposes only.
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Showing 23 of 111 compounds (12 with full profiles)
Oral ghrelin-receptor agonist developed for cancer cachexia; approved in Japan as Adlumiz.
Oral non-peptide ghrelin-receptor agonist; FDA-approved as a veterinary appetite stimulant.
CJC-1295 is a synthetic analogue of growth hormone-releasing hormone (GHRH) with amino-acid substitutions that extend its plasma half-life.
Synonym/older spelling for Hexarelin; potent GH secretagogue with cardioprotective signaling.
Follistatin is an activin-binding glycoprotein that functions as a natural antagonist of myostatin and activin signaling via TGF-beta family pathways.
Native 44-aa hypothalamic GHRH; parent molecule of sermorelin, CJC-1295, and tesamorelin.
First-generation growth hormone-releasing hexapeptide; precursor to GHRP-2/-6.
GHRP-2 (pralmorelin) is a synthetic hexapeptide growth hormone secretagogue that activates the GHSR-1a receptor, stimulating GH release from the pituitary with greater potency than GHRP-6.
GHRP-6 is a synthetic hexapeptide GH secretagogue that potently stimulates the GHSR-1a receptor (ghrelin receptor), triggering pulsatile GH release.
Gonadorelin binds the GnRH receptor on pituitary gonadotrophs, a Gq-coupled receptor that activates phospholipase C and downstream calcium and PKC signaling to drive synthesis and secretion of LH and FSH.
HCG shares its alpha subunit with LH, FSH, and TSH and carries a distinct beta subunit that binds the LH/hCG receptor with high affinity.
Hexarelin is a synthetic hexapeptide growth hormone secretagogue that acts as a potent GHSR agonist with additional binding at cardiac CD36 receptors.
Growth Hormone Essentials.
Truncated IGF-1 with localized hypertrophic action; favored for site-specific bodybuilding research.
Insulin-like Growth Factor 1 (IGF-1) is a 70-amino-acid single-chain peptide primarily secreted by the liver in response to GH stimulation.
Ipamorelin is a synthetic pentapeptide that acts as a selective growth hormone secretagogue receptor (GHSR) agonist.
Pre-blended GH-stack vial; one injection, both peptides, popular 5+5 mg ratio.
Investigational blend pairing a clean GHRP (ipamorelin) with a stable GHRH (tesamorelin).
Hypothalamic peptide that triggers natural LH surge, a clean alternative to hCG/clomid stim.
IGF-1Ec splice variant released by mechanical loading; activates muscle satellite cells.
MK-677 (Ibutamoren) is an orally active small-molecule GH secretagogue that mimics ghrelin by binding GHSR-1a, stimulating pulsatile GH release and secondarily raising IGF-1.
Sermorelin (GHRH 1-29 NH2) corresponds to the first 29 amino acids of endogenous growth hormone-releasing hormone and has been studied for its ability to stimulate pulsatile GH secretion from the anterior pituitary.
SLU-PP-332 is a synthetic agonist of the estrogen-related receptors (ERR-alpha, beta, gamma), orphan nuclear receptors that regulate mitochondrial biogenesis and oxidative metabolism in skeletal muscle.